Roderick MacKinnon: Electricity in Biology Lecture from “Electricity in Biology” at University of Minnesota, United States
- Posted on
- 01.10.2007
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- Event Details
Supplimentary Materials
Chapter 2 of 13: Responding to Music
MacKinnon illustrates the complexity of the electrical system in our bodies with a Bach cello suite played by Jacqueline du Pré. (4 minutes, 50 seconds)
Chapter 1 of 13: Electricity in Biology
Roderick MacKinnon begins his lecture by asking: How does information travel from the brain to the muscles in your finger? (4 minutes, 50 seconds)
Chapter 2 of 13: Responding to Music
MacKinnon illustrates the complexity of the electrical system in our bodies with a Bach cello suite played by Jacqueline du Pré. (4 minutes, 50 seconds)
Chapter 3 of 13: Animal Electricity
Luigi Galvani discovered that frog muscles contract when they are touched by a metal rod that carries a spark. (4 minutes, 50 seconds)
Chapter 4 of 13: Storing Charge
Early experiments with the Leiden jar and Franklin mirror. (4 minutes, 50 seconds)
Chapter 5 of 13: Is There Animal Electricity?
Further experiments with the Leiden jar, and the Galvani-Volta controversy over the source of electricity in the frog muscle contraction experiments. (4 minutes, 50 seconds)
Chapter 6 of 13: Controversy Resolved
James Clerk Maxwell and his unifying theory of electricity, magnetism and light. How Galvani was eventually proved correct about animal electricity. (4 minutes, 50 seconds)
Chapter 7 of 13: Transport Channels
How potassium and sodium ions are pumped in and out of cells. (4 minutes, 50 seconds)
Chapter 8 of 13: Patch-Clamp Technique
How do we know that ion channels exist in the cell membrane? (4 minutes, 50 seconds)
Chapter 9 of 13: Viewing Ion Channels
MacKinnon shows how there are different ways of representing the potassium channel, depending on what features you are looking to investigate. (4 minutes, 50 seconds)
Chapter 10 of 13: Selectivity Filters
How do ion channels open and close? (4 minutes, 50 seconds)
Chapter 11 of 13: Sensors and Shape Changes
A closer look at the mechanism of voltage-dependent channels reveals a sophisticated process for transporting ions in and out of cells. (4 minutes, 50 seconds)
Chapter 12 of 13: Future Applications
A deeper knowledge of ion channel structure and function will help to design and create new therapeutic compounds for ion-channel-related diseases, such as epilepsy and hypertension. (4 minutes, 50 seconds)
Chapter 13 of 13: Artificial membranes
One field of research that MacKinnon is particularly interested in is constructing synthetic materials that contain biological membranes and channels, but he admits that we know very little about the cell membrane. (4 minutes, 50 seconds)
Description
Roderick MacKinnon traces how scientists progressed from understanding electricity in physics to understanding processes like nerve impulses in animals.
